Once you have all your ingredients, it's time to mix them together. In a medium-sized bowl, whisk together the mayonnaise, ketchup, Worcestershire sauce, hot sauce, honey, lemon juice, garlic powder, and onion powder. Make sure all the ingredients are well combined and there are no lumps.

Now that your sauce is mixed, it's time to adjust the seasoning to your taste. Give the sauce a taste and add more hot sauce or honey if you want it spicier or sweeter. If it's too tangy, you can add a little more mayonnaise to mellow it out. Remember, cooking is all about experimenting and finding what works for you, so don't be afraid to adjust the seasoning to your liking.

Once your sauce is mixed and seasoned to your liking, cover the bowl with plastic wrap and refrigerate it for at least an hour. This will allow the flavors to meld together and the sauce to thicken up a bit.